Brain Natriuretic Peptide (BNP), also known as B-type Natriuretic Peptide, has important pathophysiological significance, it can promote sodium excretion, urination, has a strong vasodilating effect, can resist renin~angiotensin~aldosterone system (RAAS) vasoconstriction, like ANP is a major endocrine system of the human body against volume overload and hypertension. Cardiac dysfunction greatly activates the natriuretic peptide system, and increased ventricular load leads to BNP release.